In vitro modeling allows you the evaluate the gut related health impact of foods, their components and food structures on:
Digestion is modelled using INFOGEST-upper GI model:
Microbiota fermentation using colon models:
In vitro cell models:
Modeling |
UEF |
UH |
UTU |
VTT |
Luke |
Cell lines - gut barrier function |
x |
x |
|
|
|
Full gastrointestinal |
|
|
|
|
x |
Screening and searching (static) |
|
|
|
x |
|
Mechanisms (static & semidynamic) |
x |
x |
x |
x |
x |
Validation (dynamic) |
x |
|
|
|
x |
In vivo modelling allows you to study actual physiological responses related to the target food, food component or diet and dietary pattern either in humans or animals.
Human interventions are available for studies of acute, semi long term and long term exposures for foods, food components and diets as well as cohort studies for population based exposures. We offer possibility for multicenter studies in various populations, including populations with sensitivities, risks of diseases or actual disease. Various focus can be added in collaboration with other Platforms, such as PT1 Food processing, PT5 Sensory & consumer research, PT6 Food consumption & nutrient intake.
Human intervention can be designed to provide information on
Partners offer also services based on their expertise:
Approaches with specific populations groups:
Human intervention |
UEF |
UH |
UTU |
Population based cohort studies with various exposure |
x |
x |
x |
Postprandial (meal) studies for acute approaches (collaboration with sensory evaluation) |
x |
|
x |
Interventions of variable duration for different outcomes |
x |
x |
x |
In addition, some question may need animal models to be used:
Animal models |
UEF |
UH |
Luke |
Screening of food impact |
x |
x |
|
Disease development |
x |
x |
|
Food safety |
x |
|
|
DIAAS |
x |
|
x |
Services are available by FOODNUTRI partners at different locations by University of Eastern-Finland (UEF), Natural Research Institute (Luke), University of Helsinki (UH), University of Turku (UTU), and VTT. Contract work by service only is available for food business operators and other interested parties.
Service provider |
Location |
More information |
UEF |
Kuopio |
|
Luke |
Jokioinen |
|
UTU, Dept of Life Technologies, Food Sciences Unit UTU, Functional Foods Forum |
Itäinen pitkäkatu, Turku |
|
UH, Dept of Food and Nutrition |
Agnes Sjöberginkatu 2, Helsinki (Viikki) |
https://www.helsinki.fi/en/researchgroups/molecular-nutrition |
VTT |
Tekniikantie 21, Espoo |
https://www.vttresearch.com/en/technology-infrastructures/food-technology |